Bioactive Small Molecules
Selleck Chemical LLC Tenuifolin S9087-1MG
Tenuifolin a secondary saponin isolated from hydrolysates of polygalasaponins inhibits beta-amyloid synthesis in vitro and has nootropic activity in vivo via acetylcholine esterase inhibition and increases norepinephrine and dopamine production
Selleck Chemical LLC Tegaserod E4976-100MG
Tegaserod is an orally active agonist of serotonin receptor 4 (5-HT4R) and also acts as an antagonist of 5-HT2B receptor with pKi values of 7 5 8 4 and 7 0 for human recombinant 5-HT2A 5-HT2B and 5-HT2C receptors respectively Tegaserod has anti-tumor activity and is used in the research of irritable bowel syndrome (IBS)
AdipoGen 1-(2,5-Dichloro-3,6-dimethylphenyl ethanone (5 g)
Chemical. CAS: 164165-77-9. Formula: C10H10Cl2O. MW: 217.1. Synthetic. Building block and intermediate for synthesis. Used for the synthesis of fluorescent dyes, such as chlorofluoresceincarboxylic acids.
Selleck Chemical LLC Afuresertib hydrochloride E4992-5MG
Afuresertib hydrochloride (GSK 2110183 hydrochloride) is an orally bioavailable selective ATP-competitive and potent pan-Akt kinase inhibitor with Kis of 0 08/2/2 6 nM for Akt1/Akt2/Akt3 respectively
TARGETMOL CHEMICALS INC ROFLEPONIDE 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. Rofleponide is a synthetic glucocorticosteroid with a high affinity for the rat thymus glucocorticoid receptor. purity: 99%
Cayman Chemical SalvIa offIcnals Rosmnol 5mg
A polyphenol with diverse biological activities; an inhibitor of α-glucosidase and α amylase (IC50s = 16.4 and 40.9 UG/ml, respectively); induces apoptosis in COLO 205 cells (IC50 = ~42 µM); inhibits LPS-induced PGE2 production, as well as reduces LPS-induced NF-κB, iNOS, and COX-2 activity, in RAW 264.7 macrophages at 2.5 and 5 µM; has antinociceptive, antidepressant-like, and anxiolytic-like activity in mice at 30-100 mg/kg, respectively
Medchemexpress LLC Tixocortol-21-pivalate | 55560-96-8 | 96.8% | 462.64 g·mol⁻¹ | C26H38O5S | 5 MG
Tixocortol pivalate is a synthetic corticosteroid used in research for its anti-inflammatory properties. It is provided as a purified solid for in vitro pharmacology and allergy/contact-sensitivity studies and should be stored under controlled refrigerated or frozen conditions.
Medchemexpress LLC GPR17 antagonist 1 | 1574405-61-0 | 99.0% | 384.86 | 5 MG
GPR17 antagonist 1 (compound 978) is a GPR17 antagonist used in the study of diabetes and obesity.
- GPR17 antagonist
- Used in diabetes and obesity research
- High purity of 98.95%
- CAS number: 1574405-61-0
- Molecular weight: 384.86
- Solid, white to off-white appearance
- Soluble in DMSO for in vitro studies
- Soluble in 10% DMSO and 90% corn oil for in vivo studies
- Targets transmembrane glycoprotein
- Relevant to immunology and inflammation pathways
- Stable as powder for up to 3 years at -20°C
- Stable in solvent for up to 6 months at -80°C
Medchemexpress LLC Xylose-1-13C | 70849-21-7 | 331104 | 151.12 | 25 MG
Xylose-1-13C is a ¹³C labeled xylose, a stable heavy isotope that can be incorporated into drug molecules as a tracer for quantitation during drug development. It is intended for research use by experienced personnel in appropriately equipped facilities and is not fully validated for medical applications. The chemical, physical, and toxicological properties have not been completely investigated.
- Acts as a tracer for quantitation during drug development.
- Potential to affect pharmacokinetic and metabolic profiles of drugs (as an isotope-labeled compound).
- Suitable for laboratory chemical applications.
- For research use only.
Medchemexpress LLC GABA B Receptor 2 Antibody (YA1733) | 10 UL
GABA B Receptor 2 Antibody (YA1733) is a Rabbit-derived, non-conjugated IgG monoclonal antibody targeting GABA B Receptor 2. It is for research use only and reacts with Human, Mouse, and Rat species. It is supplied as a liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
- Rabbit-derived and non-conjugated IgG monoclonal antibody
- Targets GABA B Receptor 2
- Reactivity with Human, Mouse, Rat
- Available in multiple sizes
- Endogenous sensitivity
- Affinity Chromatography purity
- Unmodified
Medchemexpress LLC Lenalidomide-C5-NH2 TFA | 2550398-71-3 | 98.9% | 100MG
Lenalidomide-C5-NH2 TFA | 2550398-71-3 | 98.9% | 100MG
![Medchemexpress LLC 5-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)-2H-pyrazolo[3,4-c]pyridazin-3-amine | 865362-74-9 | 99.9% | 1 ML](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000230142.png-250.jpg)
Medchemexpress LLC 5-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)-2H-pyrazolo[3,4-c]pyridazin-3-amine | 865362-74-9 | 99.9% | 1 ML
FR 180204 is an ATP-competitive, selective inhibitor of ERK1 and ERK2 used for in vitro research. It inhibits ERK1 and ERK2 with IC50s of 0.51 μM and 0.33 μM, respectively, and is supplied as a solid or as a 10 mM solution in DMSO.
- ATP-competitive ERK1/2 inhibitor with low-micromolar potency.
- Suitable for biochemical and cell-based assays.
- Available as a solid or 10 mM solution in DMSO.
- High purity (≈99.9%).
- Recommended storage preserves stability under specified conditions.
Cayman Chemical ANTIBODY MDK35833 500mg
An inducer of Oct3/4 expression; induces Oct3/4 expression in reporter assays using HEK or NCCIT cells at 10 µM; induces expression of the genes encoding the pluripotency-associated proteins NANOG, REX1, and KLF4 in primary human fibroblasts at 20 µM
Cayman Chemical 5-fluoro APINAC 5mg
A synthetic CB whose physiological and toxicological properties are not known
Cayman Chemical 1 4-Dicaffeoylquinic acid 5MG
A polyphenol with diverse biological activities; scavenges DPPH radicals; inhibits XO (IC50 = 7.36 µM); decreases protein levels of tyrosinase and MITF in B16/F1 murine melanocytes, inhibits melanogenesis in the same cells, and decreases tyrosinase activity in cell lysates at 25 µM; increases biliary flow in rats